Understanding the difference between an Advanced Practice Registered Nurse (APRN) and a Nurse Practitioner (NP)
- Amira I. Quarles – AIQU

- Aug 17, 2024
- 5 min read
Updated: Dec 11, 2024
Choosing a healthcare provider can be confusing, especially when deciding between an Advanced Practice Registered Nurse (APRN) and a Nurse Practitioner (NP). Both roles are crucial in the healthcare system, but they differ in scope, specialization, and responsibilities. Both are highly trained professionals, but their roles, education, and scope of practice differ. Here’s what you need to know to make an informed decision.
Advanced Practice Registered Nurse (APRN):
An APRN is an umbrella term that encompasses four primary roles within advanced nursing practice: Nurse Practitioners (NPs), Clinical Nurse Specialists (CNSs), Nurse Anesthetists (CRNAs), and Nurse Midwives (CNMs).
Education: APRNs must have a Master’s degree in Nursing (MSN) or Doctor of Nursing Practice (DNP).
Scope of Practice: APRNs are highly trained in a specific area of practice, which allows them to perform advanced assessments, make diagnoses, manage patient care, and prescribe medications. However, the scope of practice can vary significantly depending on the specific role (e.g., an NP as a Primary Care Provider versus a CRNA working in anesthesia) and state regulations.
Specializations: APRNs can specialize in various areas such as family practice, pediatrics, geriatrics, mental health, anesthesia, or women’s health, depending on their training and certification.

Nurse Practitioner (NP):
A Nurse Practitioner (NP) is a specific type of APRN who provides direct patient care, often serving as a primary care provider.
Education and Certification
NPs must complete a Master of Science in Nursing (MSN) or a Doctoral degree in Nursing (DNP). Their advanced clinical training goes beyond their initial Registered Nurse (RN) preparation, equipping them to diagnose, treat, and manage a wide range of conditions.
Scope of Practice
NPs are trained to assess, diagnose, treat, and manage acute and chronic illnesses. They can order and interpret diagnostic tests, prescribe medications, and initiate treatment plans. In many states, NPs have full practice authority, meaning they can operate independently without physician oversight.
Specializations
NPs often specialize and focus on specific populations or types of care.
Family Nurse Practitioner (FNP): Provides care across all ages, from infants to seniors.
Pediatric Nurse Practitioner (PNP): Focuses on children’s health, including preventive care and chronic disease management.
Women’s Health Nurse Practitioner (WHNP): Specializes in gynecology, reproductive health, and family planning.
Adult-Gerontology Nurse Practitioner (AGNP): Manages the health needs of adults and elderly patients.
How Are APRNs and NPs Different?
Key Differences:
Broader Role for APRNs
While all Nurse Practitioners (NPs) are APRNs, not all APRNs are NPs. Other advanced nursing roles include:
CRNAs: Experts in anesthesia, ability to administer anesthesia and pain management.
CNMs: Specialists in women’s health and childbirth (midwifery).
Primary Care Expertise for NPs
NPs are best known for providing holistic and patient-centered care. While all APRNs may engage in direct patient care, NPs are particularly known for providing comprehensive care and often serve as primary care providers. Their focus on overall wellness and chronic condition management makes them a trusted choice for long-term care, especially in areas with physician shortages.
Why This Distinction Matters
Choosing between an APRN and an NP depends on your healthcare needs and the type of patient centered care that is necessary.
If you’re looking for general healthcare, management of chronic conditions, or primary care– an NP might be an excellent fit due to their direct patient care focus.
If you need specialized care, such as anesthesia or midwifery, other types of APRNs such as a CRNA or CNM may be more appropriate.
Nurse Practitioners and Patient-Centered Care
In summary, all NPs are APRNs, but not all APRNs are NPs.
Each role within the APRN category serves different purposes in the healthcare system.
Nurse Practitioners are key providers of direct patient centered care in various specialties. They combine medical expertise with compassionate, individualized care, making them invaluable in managing acute illnesses, chronic conditions, and preventive health.
Ultimately, Patient-Centered Care Benefits are often seen with Holistic Health Practitioners – NPs provide care that looks at the whole person, not just their symptoms.
For more insights into the benefits of NP-led care, visit our blog:
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How Nurse Practitioner-Led Care Works in Pennsylvania
Restricted Authority in Pennsylvania
In Pennsylvania, Nurse Practitioners must maintain a collaboration agreement with a physician. This agreement outlines the partnership between the NP and MD for specific scenarios. However, it does not interfere with the NP’s ability to provide direct patient care or manage chronic conditions.
Pending Legislation in Pennsylvania
While Nurse Practitioners in Pennsylvania currently operate under restricted authority, pending bills in the state legislature aim to promote full practice authority. If passed, this would remove the requirement for physician collaboration, increasing access to NP-led care for patients across the state.
At Tried and True Weight Loss, Amira I. Quarles, CRNP, MSN, works under such an agreement with a collaborating MD, a previous colleague from her time as a cardiovascular Nurse Practitioner managing her own patient panel. This collaboration ensures that if acute care discussions arise, a trusted physician is available for consultation.
Let us guide you on the path to sustainable weight management. Visit Tried and True Weightloss or message us to learn more about how we can support your goals. Here’s to a balanced, vibrant, and healthier you!
Amira I. Quarles is a Certified Nurse Practitioner (CRNP) based in Pittsburgh, PA, and licensed to provide care and prescribe medications in South Dakota. With advanced education and clinical expertise, Amira specializes in GLP-1 weight loss injections, medical weight loss management, and holistic care for diverse patient populations. With a holistic approach to weight loss and wellness, she is committed to helping patients achieve their health goals through personalized care.

For those interested in getting to know Amira and her approach to wellness and weight management, please visit our weight loss clinic website to Get to know more about Amira I. Quarles, CRNP.
You can also connect with Amira on LinkedIn to learn more about her background and philosophy on wellness via Amira’sLinkedIn Profile.












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